We present a case of generalized grannuloma annulare with perforating and subcutaneous forms which occurreed in a 15-year-old girl. Two years ao, multiple umbilicated, match head to pea sized, erythematous papules were noted on the upper
extremities.
Then the patient also experineced crusted or ulcerated erythematous papular lesions on the lower legs. Recently, tender, sudcutaneous nodules appeared on both soles. The biopsy specimens from the skin lesions of the hand and the sole showed
typical
findings of granuloma annulare in the skin lesions o the hand and the sole showed typical findings of granuloma annulare in the dermis and the subcutis, respectively. On the histopathological examination of the calf lesion, palisading granuloma
as
well
as trasepidermally eliminating dermal collagenous and necrotic material were seen. The skin lesions were almost completely improved by treatment with sdapsone, 100mg a day, for 8 weeks orally. (Kor J Dermatol 1995;33(6) : 1119~1123)
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